meRfi®-GM
CD40 (Tumor necrosis factor receptor superfamily member 5)
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CD40 = DC receptor
CD40 is a co-stimulatory TNF receptor that is constitutively expressed on antigen-presenting cells and B cells and its ligand, CD40L, is expressed on T cells
CD40-activated macrophages rapidly infiltrate tumors, become tumoricidal, and facilitate the depletion of tumor stroma…