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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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CD40 (Tumor necrosis factor receptor superfamily member 5)

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CD40 = DC receptor
Hesse et al., 2013

CD40 is a co-stimulatory TNF receptor that is constitutively expressed on antigen-presenting cells and B cells and its ligand, CD40L, is expressed on T cells

CD40-activated macrophages rapidly infiltrate tumors, become tumoricidal, and facilitate the depletion of tumor stroma…

References (Sources)

CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells
Lu et al. 2022d J Immunol 209(11): 2083-2092
In vivo targeting of human DC-SIGN drastically enhances CD8+ T-cell-mediated protective immunity
Hesse et al., 2013

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12/16/2025

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CD40 (Tumor necrosis factor receptor superfamily member 5)

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