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Rheumatoid Arthritis (RA)
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Contents
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints. Autoantibodies (auto-Abs) play a critical role in the pathogenesis of RA by contributing to immune complex formation and complement activation, which leads to tissue damage in the joints
NFKB Activation contributes to the chronic inflammation and joint destruction characteristic of this [autoimmune disease](brain://IywEh…
References (Sources)
- Depression risk in patients with rheumatoid arthritis in the United Kingdom
- Hemolytic Complement in Synovial Fluid
- Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cells
- Rheumatoid arthritis
- The complement system in rheumatoid synovitis. I. An analysis of complement component activities in rheumatoid synovial fluids
- The complement system in rheumatoid synovitis. II. Intracytoplasmic inclusions of immunoglobulins and complement
- The global burden of rheumatoid arthritis: estimates from the global burden of disease 2010 study