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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Butyrate / Butyric acid & Sodium-Coupled Monocarboxylate Transporter 1 (SMCT1)

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The SLC5A8 / Sodium-Coupled Monocarboxylate Transporter 1 (SMCT1) mediates [Butyrate / Butyric acid](brain://E42jsss5J0Kk0Df0jHlQLg/Butyrat…

Identification of a structural requirement for thyroid Na+/I- symporter (NIS) function from analysis of a mutation that causes human congenital hypothyroidism
Levy et al. 1998 FEBS Lett. 429: 36-40
Microbiota metabolite short-chain fatty acids (SCAFs), GPCR, and inﬂammatory bowel diseases
Sun et al. 2017
SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter
Gupta et al. 2006 Life Sci 78(21): 2419-25
Review
Slc5a8, a Na+-coupled high-afﬁnity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and CRC under low-ﬁbre dietary conditions
Gurav et al. 2015 Biochem J. 469(2): 267-278

5/29/2026