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Alzheimer's Disease (AD) & Pathogenicity

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Peripheral immune cells are crucial in the pathology of Alzheimer’s disease (AD), influencing key processes such as amyloid and tau protein aggregation, glial activation, neuronal integrity, and cognitive decline.
Lin et al. 2024 Trends in Immunology 45(12): 971

Amyloid-beta (Ab), tau, and Apolipoprotein E (APOE) are significant players in the pathogenesis o…