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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Pro-Interleukin-1 (IL-1) beta (IL-1 beta)

Contents

Pro-Interleukin-1 (IL-1) beta (IL-1 beta) is the inactive precursor form of the potent pro-inflammatory cytokine Interleukin-1 (IL-1) beta (IL-1F2), consisting of 269 amino acids
Hailey et al. 2009 J Biol Chem 284(38): 26137-48
Lopez-Castejon & Brough 2011 Cytokine Growth Factor Rev 22(4): 189-95

References (Sources)

A Molecular Platform Triggering Activation of Inflammatory Caspases and Processing of proIL-β
Martinon et al. 2002 Mol Cell 10: 417-426
Pro-interleukin (IL)-1beta shares a core region of stability as compared with mature IL-1beta while maintaining a distinctly different configurational landscape: a comparative hydrogen/deuterium exchange mass spectrometry study
Hailey et al. 2009 J Biol Chem 284(38): 26137-48
Understanding the mechanism of IL-1β secretion
Lopez-Castejon & Brough 2011 Cytokine Growth Factor Rev 22(4): 189-95
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