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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Biological effects / Functions & Secondary bile salts / Secondary bile acids (SBAs)

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Approximately 95% of the intestinal bile acids are absorbed in the ileum via apical sodium bile acid co-transporter (ASBT) and regulate

the secretion of gastrointestinal hormones (e.g., Glucagon Like Peptide 1 (GLP-1),

Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia, and nonalcoholic fatty liver disease
Chávez-Talavera et al. 2017 Gastroenterology 152(7): 1679-94
Review
Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract
Foley et al. 2019 PLoS Pathog. 15: e1007581
Gut microbiome and cardiometabolic risk
Kappel & Federic 2019 Reviews in Endocrine and Metabolic Disorders 20: 399-406
Review
Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis
Song et al. 2019b Nature 577(7790): 410-415
Role of Bile Acids in the Regulation of Food Intake, and Their Dysregulation in Metabolic Disease
Xie et al. 2021a
Review

5/29/2026