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KRAS is the most frequently mutated oncogene.
Hofmann et al. 2022 Cancer Discov 12: 924-37
KRAS is the most frequently mutated in human cancers of the three RAS family members.
Johnson et al. 2022a Cancer Discov 12: 913-23
KRAS mutations are seen in approx. 1/7 cancers.
Hofmann et al. 2022 Cancer Discov 12: 924-37
KRAS is frequently mutated in cancer, and its overactivation can lead to oncogene-induced senescence (OIS), a barrier to cell transformation.
[Shui et al. 2022 Trends in Cancer 8: 384](brain://GT…