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Immune responses
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Immune responses to foreign and self-antigens require specific and balanced responses to clear pathogens and tumors and yet maintain tolerance.
The selectivity of the immune response is dictated by sensors that recognize the stimulus, by the downstream signaling pathways, and by the transcriptional and chromatin regulators activated by these pathways.
Different types of immune responses are specialized based on the type of pathogen:
- [Type …
References (Sources)
- Adaptation and memory in immune responses
- CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut
- Impact of oncogenic pathways on evasion of antitumour immune responses
- Molecular control of activation and priming in macrophages
- PD-1 and Its Ligands in Tolerance and ImmunityReview
- The selection and function of cell type-specific enhancers
- Transcriptional determination and functional specificity of myeloid cells: making sense of diversity