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Acute graft-versus-host disease (aGVHD) remains a major limitation of allogeneic stem cell transplantation (SCT), and severe intestinal manifestation is the major cause of early mortality
During the first step, which is associated with tissue damage, pro-inflammatory cytokines, such as tumor necrosis factor-alfa (TNF-alfa) or interleukin-1, are released.
After the Acute…