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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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AuthorsReferences (Sources)

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Galactooligosaccharides (GOS)

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Galactooligosaccharides (GOS) are soluble fibres and derived from lactose which are digested by, and result in the proliferation of, the Lactobacilli and Bifidobacteria in the gut.
Savignac et al. 2013 Neurochem. Int. 63: 756–764

Supply of galactooligosaccharides promotes host health:

Selective fermentation to produce Short-chain fatty acids (SCFAs)

Antimicrobial factors increased

Increased beneficial Bifidobacterium and decreased pathogenic [Clostridium histolyticum / Hathewaya histolytica](brain://eurENgiQJU6x…

References (Sources)

A probiotic mixture including galactooligosaccharides decreases fecal β-glucosidase activity but does not affect serum enterolactone concentration in men during a two-week intervention
Kekkonen et al. 2011 J Nutr 141: 870-876
Administration of transgalacto-oligosaccharides increases fecal bifidobacteria in healthy humans
Bouhnik et al. 1997 J. Nutr. 127(3): 444-8
Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics
Macfarlane et al. 2008 J Appl Microbiol 104:305–44.
Review
Modulation of the fecal microﬂora proﬁle and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers
Vulevic et al. 2008 Am J Clin Nutr 88: 1438–1446
Prebiotic feeding elevates central brain derived neurotrophic factor, n-methyl-d-aspartate receptor subunits and d-serine.
Savignac et al. 2013 Neurochem. Int. 63: 756–764
Prebiotic potential of a maize-based soluble fibre and impact of dose on the human gut microbiota
Costabile et al. 2016
Understanding the role of gut microbiome–host metabolic signal disruption in health and disease
Holmes et al. 2011
Review

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Galactooligosaccharide - Wikipedia