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PYY and GLP-1 have also been shown to inhibit the motility of the upper gastrointestinal (GI) tract. This slows the gastric emptying of ingested foods and prolongs the stimulation of mechanoreceptors and chemoreceptors in the GI tract that signal centrally via [vagal afferents](brain://KMvWwRQH-USOKrt1iiRg4A/ParasympatheticNervousSystemParasympathicusVag…