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Radiation therapy is the most prevalent source of radiation. It is extensively utilized in medical diagnostics and cancer treatment
Radiation therapy can increase neoantigen expression, increase tumor PD-L1 expression, increase MHC class I indication, reverse depleted CD8 T cells, and increase tumor-infiltrating tumors within the tumor microenvironment
Tubin et al. 2020 Future Oncology 16: 1137-1151
These changes in tumor and tumor microenvironment after radiotherapy could enhance responses to anti-CTL-4, anti-PD-L1/PD1, and other immunotherapeutic agents
Tubin et al. 2020 Future Oncology 16: 1137-1151
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