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Radiation / Radiotherapy (RT)
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Contents
Radiation therapy can increase neoantigen expression, increase tumor PD-L1 expression, increase MHC class I indication, reverse depleted CD8 T cells, and increase tumor-infiltrating tumors within the tumor microenvironment
Tubin et al. 2020 Future Oncology 16: 1137-1151
These changes in tumor and tumor microenvironment after radiotherapy could enhance responses to anti-CTL-4, anti-PD-L1/PD1, and other immunotherapeutic agents
Tubin et al. 2020 Future Oncology 16: 1137-1151…
References (Sources)
- Current increase and the emerging efficacy of strategies radiation in the treatment cancerReview
- Evolution in the management of soft tissue sarcoma: classification, surgery and use of radiotherapy
- Phase II investigational oral drugs for the treatment of radio/chemotherapy induced oral mucositisReview
- Presentation of antigen by B cells: functional dependence on radiation dose, interleukins, cellular activation.,and differential glycosylation
- Radiation therapy and immunotherapy: what is the optimal timing or sequencing?Review
- Whole-Brain Radiation for Brain Metastases: Evolution or Revolution?Review