Radiation / Radiotherapy (RT)

Radiation therapy is the most prevalent source of radiation. It is extensively utilized in medical diagnostics and cancer treatment
Li et al. 2025 Gut Microbes 17(1): 2528429

Radiation therapy can increase neoantigen expression, increase tumor PD-L1 expression, increase MHC class I indication, reverse depleted CD8 T cells, and increase tumor-infiltrating tumors within the tumor microenvironment
Tubin et al. 2020 Future Oncology 16: 1137-1151

These changes in tumor and tumor microenvironment after radiotherapy could enhance responses to anti-CTL-4, anti-PD-L1/PD1, and other immunotherapeutic agents
Tubin et al. 2020 Future Oncology 16: 1137-1151