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Antibodies / Immunoglobulins are produced in B cells / B Lymphocytes
Antibodies have become the most successful class of biologic drugs for treating indications ranging from autoimmune and neurodegenerative diseases to cancer and infectious disease
Hanning et al. 2022 Trends in Pharmacological Sciences 43: 123
The unmistakable influence of these molecules on modern medicine is highlighted by the recent milestone approval of the 100th monoclonal antibody (mAb; see Glossary) drug by the FDA [1,2].
Hanning et al. 2022 Trends in Pharmacological Sciences 43: 123
Despite their success, there are still many unmet medical needs requiring the development of next-generation antibodies with higher affinity, greater specificity, improved stability, and enhanced immune functionality
Hanning et al. 2022 Trends in Pharmacological Sciences 43: 123