Phagocytes

These cells, recognize, ingest, and kill cellular microbes by the process of phagocytosis and intracellular pathogens by the process of Autophagocytosis / Autophagy (or autophagy)
Willey et al. 2023 McGraw Hill, USA, ISBN 978-1-265-12303-1

The microorganisms are recognized

• by Opsonization / Opsonin


• by their unique molecules (MAMPs)

Willey et al. 2023 McGraw Hill, USA, ISBN 978-1-265-12303-1

Mononuclear phagocytes are also indispensable for host defense against systemic C. albicans infection
Legrand et al. 2008 Clin. Infect. Dis. 46: 696-702
Lionakis et al. 2013 J. Clin. Invest. 123: 5035-5051
Ngo et al. 2014 J. Infect. Dis. 209: 109-119

For example, Ly6C+ monocytes and CX3CR1+ macrophages can directly phagocytose fungi and help neutrophils eliminate fungi indirectly by mediating tissue inflammation
Legrand et al. 2008 Clin. Infect. Dis. 46: 696-702
Majer et al. 2012 PLoS Pathog. 8: e1002811
Lionakis et al. 2013 J. Clin. Invest. 123: 5035-5051
Ngo et al. 2014 J. Infect. Dis. 209: 109-119
Domínguez-Andrés et al. 2017 Immunity 46: 1059-1072

see also:
Candidiasis
Microbial associated molecular patterns (MAMPs)
Opsonization / Opsonin
Phagocytic Activity / Phagocytosis