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Arginase II is one of two mammalian arginase isozymes. It is a mitochondrial enzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea . Arginase II is a mitochondrial enzyme involved in arginine metabolism , with important roles in regulating nitric oxide production, immune cell function, and inflammation. Its activity is critical in extra-hepatic tissues, especially the kidney, and it is a key player in the resolution of inflammati…