Proteome

Since the first essentially complete eukaryotic proteome was described (1), advances in mass spectrometry-based proteomics (2) have enabled increasingly comprehensive identification and quantification of the human proteome (3-6).
Müller et al. 2020

A remarkably high proportion of the total proteomic mass in all kingdoms is devoted to protein homeostasis and folding, underscoring the physical challenge of maintaining protein structure in all branches of life.
Müller et al. 2020

Likewise, a consistently high proportion is involved in providing energy resources, with these pathways ranging from photosynthesis to iron-sulfur metabolism and carbohydrate metabolism.
Müller et al. 2020