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Clostridioides difficile infection (CDI)

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Clostridioides difficile (CDI) intestinal infections are among the most common nosocomial infections in high-income countries

Clostridioides difficile infection (CDI) is a common infection acquired in hospitals in the USA. It affects 500,000 people each year and results in healthcare costs that surpass $1.5 billion.
Guh et al. 2020 N Engl J Med 382: 1320-1330
CDC 2022 Educational resources (Centers for Disease Control and Prevention). https://www.cdc.gov/cdiff/materials.html.

Enterococci enhance the fitness and pathogenesis of Clostridioides difficile in the gut by altering the amino acid composition and providing signals that increase its virulence towards the host
Smith et al. 2022b Nature 611: 780

Clostr…