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Panton-Valentine leukocidin (PVL) is a cytotoxin produced by certain strains of Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA).
Panton-Valentine leukocidin (PVL) forms pores in the membranes of host immune cells, particularly neutrophils, leading to cell lysis and death. This toxin is associated with severe skin infections and necrotizing pneumonia.
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