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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Natural Killer T cell (NKT-Cell)

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Natural Killer T cell (NKT-Cell) are a distinct population of T lymphocytes that display features characteristic of NK cells and conventional T cells / T lymphocytes
Fowlkes et al. 1987 Nature 329: 251-254
Makino et al. 1995 Int Immunol 7: 1157-1161
Godfrey et al. 2010 Nat Immunol 11: 197-206

Natural Killer T cell (NKT-Cell) recognize nonpeptide ligands, including microbial lipid antigens that are presented by several MHC class I-like proteins.
Murphy et al. 2022 W.W. Norton & Company ISBN 978-0-393-68093-5

Mouse and human Natural Killer T cell (NKT-Cell) recognize [glycosphingolipids](brain://MFB…

References (Sources)

A novel population of T-cell receptor ab-bearing thymocytes which predominantly expresses a single V b gene family
Fowlkes et al. 1987 Nature 329: 251-254
Glycolipid Stimulation of Invariant NKT Cells Expands a Unique Tissue-Resident Population of Precursors to Mature NK Cells Endowed with Oncolytic and Antimetastatic Properties
Choi et al. 2019
Janeway’s Immunobiology 10th
Murphy et al. 2022 W.W. Norton & Company ISBN 978-0-393-68093-5
Predominant expression of invariant Va 14+ TCR alfa chain in NK1.1+ T cell populations
Makino et al. 1995 Int Immunol 7: 1157-1161
Raising the NKT cell family
Godfrey et al. 2010 Nat Immunol 11: 197-206
Review
Recognition of bacterial glycosphingolipids by natural killer T cells
Kinjo et al. 2005 Nature 434: 520-525
Targeting natural killer cells and natural killer T cells in cancer
Vivier et al. 2012
Review

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12/16/2025

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Natural Killer T cell (NKT-Cell)

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