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Immunologically “cold” tumors, which appear histologically to exhibit an absence of immune infiltrate or an essential immune cell subpopulation, including CD8 + T cells, are far more frequent than immunologically “hot” tumors
Chen & Mellman 2017 Nature 541: 321
Inflammatory Reprogramming with IDO1 Inhibitors: Turning Immunologically Unresponsive ‘Cold’Tumors ‘Hot’
Prendergast et al. 2018
Neutrophils/Neutrophilic Granulocytes induce inflammatory resposes also in tumor tissues (generating hot tumors)
see also:
[Tumor Immune Response](brain://Ny0ffjONgEatj2Kzka9TIQ/TumorImmuneResp…