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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Adiposity / Obesity & Short-chain fatty acids (SCFAs)

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Alterations in SCFA signaling and downstream effects on inflammation are implicated in the development of adiposity / obesity and hypertension
Overby & Ferguson 2021 Current Hypertension Reports 23: 8

In addition, SCFA also directly modulates host metabolic health through a range of tissue-specific mechanisms related to Appetite regulation, Energy expenditure, [glucose homeostasis](brain://QJC_XwzvmEeTG3BS1Hilzg/Glu…

References (Sources)

Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?
Chambers et al. 2015a Proc Nutr Soc 74: 328-36
Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation
Kasubuchi et al. 2015 Nutrients 7: 2839-2849
Review
Gut Microbiota-Derived Short-Chain Fatty Acids Facilitate Microbiota:Host Cross talk and Modulate Obesity and Hypertension
Overby & Ferguson 2021 Current Hypertension Reports 23: 8
Review
Microbiota and SCFA in lean and overweight healthy subjects.
Schwiertz et al. 2010 Obesity 18: 190-5
Short chain fatty acids in human gut and metabolic health
Blaak et al. 2020 Beneﬁc. Microbes 11: 411-455
Short-chain fatty acids and inulin, but not guar gum, prevent diet-induced obesity and insulin resistance through differential mechanisms in mice
Weitkunat et al. 2017 Scientific reports 7(1): 6109
The interaction between microbiome and host central nervous system: the gut-brain axis as a potential new therapeutic target in the treatment of obesity and cardiometabolic disease
Wijdeveld et al. 2020
Review

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Adiposity / Obesity & Short-chain fatty acids (SCFAs)

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