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AEA and 2-Arachidonoylglycerol (2-AG) are inactivated in respective target tissues differently. Indeed, AEA is hydrolyzed to AA and ethanolamine by fatty acid amide hydrolase (FAAH), whereas 2-Arachidonoylglycerol (2-AG) is mainly hydrolyzed by MAG lipase (MAGL) into AA and glycerol
Dinh et al. 2002 Proc. Natl. Acad. Sci. USA…