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Most plant lignans in the mammalian diet are converted into enterolignans in the upper part of the colon by the gut microbiota
Two enterolignans (mammalian lignans) are enterodiol (END) and enterolactone (ENL)
A diet rich in lignans can be beneficial, especially if taken throughout life. Animal experiments have shown an anti-cancer effect of flaxseed or pure lignans.
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