meRfi®-GM
Mutations in the Tail Fiber Genes
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Contents
Mutations in tail fiber genes refer to changes in the genes that code for the tail fibers of bacteriophages. The tail fibers of a bacteriophage play a crucial role in the infection process as they are responsible for recognizing and binding to the host receptor. Mutations in these genes can alter the structure of the tail fibers, potentially allowing the bacteriophage to infect a wider range of host bacteria or to bind more effectively to the host receptors. This can increase the bacteriophage's ability to establish and maintain its presence in the gut microbiome.
[Mour…
References (Sources)
- DNA sequences of the tail fiber genes of bacteriophage P2: evidence for horizontal transfer of tail fiber genes among unrelated bacteriophages
- Mapping the Tail Fiber as the Receptor Binding Protein Responsible for Differential Host Specificity of Pseudomonas aeruginosa Bacteriophages PaP1 and JG004
- Understanding Bacteriophage Tail Fiber Interaction with Host Surface Receptor: The Key "Blueprint" for Reprogramming Phage Host Range