Loading…
Please register to continue your trial period!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Its molecular weight is approx. 30 kDa, and it belomgs to galectins with 2 carbohydrate recognition domains (CRDs).
Galectin-3 (Gal-3) belongs to animal lectins defined by their high affinity for beta-galactoside
Galectin-3 contains nonlectin domain fused with the CRD (carbohydrate recognition domain)
Galectin-3 has significant sequence similarity to Bcl-2.
Liu & Rabinovich 2005
Galectin-3 exists in phosphorylated form inside the cell.
Liu & Rabinovich 2005
Phosphorylation of galectin-3 (Gal-3) is crucial for its anti-apoptotic activity (suppressor of apoptosis).
Galectin-3 (Gal-3) forms oligomers binding multiva…