Bacterial genome

The first two bacterial genomes, including that of Haemophilus influenzae, were sequenced almost 30 years ago. The cost for sequencing Haemophilus influenzae was over $1,000,000, and its determination took several years. Today, an entire bacterial genome can be sequenced in hours for less than $100. Today, over 1.9 million bacterial genomes are available in databases like AllTheBacteria, along with large amounts of information in multi-omic datasets.
Fleischmann et al. 1995 Science 269: 496-512
Fraser et al. 1995 Science 270: 397-403
Hunt et al. 2024 bioRxiv (preprint)

There are many publicly available bacterial genome sequences. Most were created using [short-read sequencing](brain://ZgdVegawtUOM1jDY_O9b…