meRfi®-GM
CD284 (Toll-Like Receptor 4 (TLR-4))
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Contents
Toll-Like Receptor 4 (TLR-4) is localized on cell membranes of CD11c + Conventional dendritic cell (cDC) / myeloid dendritic cell (mDC)), Monocytes, Basophils, Mastocytes / Mast cells
The ligands are: Lipopolysaccharides (LPS), Lipoteichoic Acid (LTA), TLR-4/CD14 agonists
[TLR-4 activation](brain:…
References (Sources)
- .01 Pattern recognition receptors: immune targets to enhance cancer immunotherapy
- Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production
- CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer
- Innate immune signaling by TLR-4 shapes the inflammatory microenvironment in colitis-associated tumors
- Recognition and signaling by Toll-like receptors
- Starring role of toll-like receptor-4 activation in the gut-liver axis
- Toll‑like receptor 4 plays a tumor‑suppressive role in cutaneous squamous cell carcinoma