meRfi®-GM
p38 MAP Kinases
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Navigation
Contents
Generally, cellular stresses and inflammatory cytokines activate p38 MAP Kinases
Four p38 MAP kinases, p38-alfa (MAPK14), -beta (MAPK11), -gamma (MAPK12 / ERK6), and -delta (MAPK13 / SAPK4), have been identified. They are involved in cell differentiation, apoptosis and autophagy.
By osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), ultraviolet light, and growth factors activated p38 MAP kinases activate transcription factors (ATF2, Mac, MEF2, p53)
…
References (Sources)
- Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model.
- Inhibition of p38mapk Reduces Adipose Tissue Inflammation in Aging Mediated by Arginase-II
- Regulation of Host Immune Responses against Influenza A Virus Infection by Mitogen-Activated Protein Kinases (MAPKs)