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Astrocytes

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Contents

Characterization


Astrocytes (almost immobile) make up at least 50% of humans' brain and spinal cord cells. Astrocytes are essential for synapse formation (3). If they provide trophic support to neurons, one cannot remove them without catastrophic consequences [4].
Liddelow et al. 2020 Trends in Immunology 41: 820

Astrocytes & Immunity/Immunomodulation


However, astrocytes have been suggested to have immunological functions in both health and disease [19,20].
Castellanii & Schwartz 2020 Trends in immunology 41: 794

Astrocytes were shown to exert both pro- and anti-inflammatory signaling functions, depending on the context.
Castellanii & Schwartz 2020 …