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Plasma cells arise from B cells / B Lymphocytes when they have come into contact with antigen (differentiation). Their role is the secretion of antibodies.
Antibody-secreting plasma cells (PCs), on the other hand, depend on the activation of PR domain zinc finger protein 1 (Blimp-1) for their terminal differentiation
The gut microbiome can influence the bone marrow microenvironment through cytokines. Plasma cells have Interleukin-17 (IL-17) receptors and are activated by [Interleukin-17 Family / Interleukin-17 (IL-17)]…