meRfi®-GM
Plasmablast / Plasma cells
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Navigation
Contents
Plasma cells arise from B cells when they have come into contact with antigen (differentiation). Their role is the secretion of antibodies.
Antibody-secreting plasma cells (PCs), on the other hand, depend on the activation of PR domain zinc finger protein 1 (Blimp-1) for their terminal differentiation
The gut microbiome can influence the bone marrow microenvironment through cytokines. Plasma cells have Interleukin-17 (IL-17) receptors and are activated by [Interleukin-17 Family / Interleukin-17 (IL-17)](brain://gxTb-ttgjlqhmWcXTkF…
References (Sources)
- A novel role of IL-17 producing lymphocytes in mediating lytic bone disease in multiple myeloma
- Cell fate dynamics and genomic programming of plasma cell precursors
- Cellular and chromatin dynamics of antibody-secreting plasma cells
- Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
- Fecal IgA Levels and Gut Microbiota Composition Are Regulated by Invariant Natural Killer T Cells
- Memory B cells and plasma cells: The differentiative continuum of humoral immunity
- Plasma cells: The programming of an antibody-secreting machine