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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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AuthorsReferences (Sources)

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Plasmacytoid Dendritic Cells (pDCs)

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Contents

Plasmacytoid Dendritic Cells (pDC) originate from a common DC progenitor (CDP) or a CD115- a subset of a common DC progenitor (CDP)
Naik et al. 2007 Nat. Immunol. 8: 1217-1226
Onai et al. 2007 Nat. Immunol. 8: 1207-1216
Onai et al. 2013 Immunity 38: 943-957

Plasmacytoid Dendritic Cells (pDCs) express markers CD11c-, CD123, CD303 (BDCA-2) and CD304 unlike other dendritic cell types and are typically identified in blood

Plasmacytoid Dendritic Cells (pDCs) specialize in releasing Interferon alfa (IFN-alfa) and Interferon beta (IFN-beta) upon recognition of viral or endogenous nucleic acids via [Toll-like receptor 7 (TLR-7)](brain://ifHT9ZJTXVGkB…

References (Sources)

A clonogenic progenitor with prominent plasmacytoid dendritic cell developmental potential
Onai et al. 2013 Immunity 38: 943-957
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo
Naik et al. 2007 Nat. Immunol. 8: 1217-1226
Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow
Onai et al. 2007 Nat. Immunol. 8: 1207-1216
Plasmacytoid Dendritic Cells: Development, Regulation, and Function
Reizis 2019 Immunity 50: 37-50
Review
The multifaceted biology of plasmacytoid dendritic cells
Swiecki & Colonna 2015 Nat. Rev. Immunol. 15: 471-485
Review
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
Kawai & Akira 2011 Immunity 34: 637-650
Review
What Makes a pDC: Recent Advances in Understanding Plasmacytoid DC Development and Heterogeneity
Musumeci et al. 2019 Front Immunol.10: 1222

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Plasmacytoid dendritic cell - Wikipedia