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Occludin plays a role in the formation and disassembly of the Tight Junction proteins and is involved in the regulation of the “leak pathway” or paracellular flux of large molecules (1, 15–17)
Kaminsky et al. 2021 Front. Immunol. 12: 767456 (1, 5, 12–14).
Among these TJ proteins, occludin always combines with the zonula occludens members ZO-1 / ZO-2 or ZO-1 / ZO-3 in the cell membrane (7).
Su et al. 2021 Inflamm Bowel Dis. 27: 1302
Occludin is also involved in the stability and regulation of Tight-Junction Molecules / Tight Junction Proteins
Occludin plays a role in the formation and disassembly of the [TJ](brain://HWvzcrmAmk67gHnHgflHkw/Tigh…