Loading…
Please register to continue your trial period!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
The unfolded protein response (UPR) serves to maintain protein homeostasis, mainly in the endoplasmic reticulum (ER). This pathway carefully responds to a variety of intracellular indicators of ER stress. The accumulation of unfolded proteins is reduced, the folding capacity of the ER is enhanced, and slowly folding proteins are eliminated
The Unfolded Protein Response (UPR) is initiated by three Endoplasmic reticulum (ER) transmembrane sensors: inositol-requiring enzyme 1 (IRE1), Protein kinase RNA-like ER kinase (PERK), and [Activating Transcription Factor 6 (ATF6)](brain://n…