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Antimicrobial peptides (AMPs)
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Antimicrobial peptides (AMPs) are promising candidates for therapeutic use and have been clinically applied as antiviral drugs, such as enfuvirtide and telaprevir. AMPs with immunomodulatory properties are currently in clinical trials. Peptides targeting yeast and bacterial infections, like pexiganan, LL-37, and PAC-113, are also under clinical evaluation.
While most Antimicrobial peptides (AMPs) have broad-spect…
References (Sources)
- Bacterial antagonism in host-associated microbial communities
- Bacteriocins — a viable alternative to antibiotics?
- Cryptic Antimicrobial Peptides: Identification Methods and Current Knowledge of their Immunomodulatory Properties
- How nature morphs peptide scaffolds into antibiotics
- Identification of natural antimicrobial peptides from bacteria through metagenomic and metatranscriptomic analysis of high-throughput transcriptome data of Taiwanese oolong teas
- Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides
- Shigella sonnei encodes a functional T6SS used for interbacterial competition and niche occupancy