meRfi® logo
Medical Research Finder
House iconIcon chat dots
Icon question circle

meRfi®-GM

Stop codon reassignments

Welcome to meRfi-GM!

meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

Contents

Stop codon reassignment refers to the process where the meaning of a stop codon is altered. In molecular biology, a stop codon is a nucleotide triplet within messenger RNA (mRNA) that signals the termination of protein synthesis. Normally, when a stop codon is encountered during the translation process, it signals the end of protein synthesis. However, in stop codon reassignment, the stop codon is reassigned to code for an amino acid instead of signaling the end of protein synthesis. This can occur due to changes in the translational apparatus, such as alteration or loss of a release factor.
Atkins & Baranov 2010 Genetics. 185(4): 1535-6
[Chen et al. 2023 Molecular Biology and Evolution 40(4): msad064](brain://OnBwe0BVlUOfWsIfrtQvZw/ChenEtAl…