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Catabolism & Cholesterol
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Contents
Cholesterol is metabolized in the intestine with the participation of the gut microbiota.
Enzymatic oxidation of cholesterol generates numerous distinct bile acids. These bile acids serve dual functions:
- As detergents that facilitate the digestion and absorption of dietary lipids.
- As hormones that activate five distinct receptors.
Primary bile acids (cholic acid (CA) and [chenodeoxycholic acid (CDCA))](brain://pCMNMJSVzk…
References (Sources)
- .01 The continuing importance of bile acids in liver and intestinal disease
- Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level
- Intestinal Bacteria Interplay With Bile and Cholesterol Metabolism: Implications on Host PhysiologyReview
- The immunomodulatory role of bile acids