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Allogeneic hematopoietic cell transplantation (allo-HCT) can be a curative therapy for patients with hematological malignancies. However, it poses a significant risk for post-transplant mortality due to graft-versus-host disease (GVHD). The number of allogeneic hematopoietic stem cell transplants performed worldwide is steadily increasing. Consequently, the absolute number of complications, particularly GVHD, also rises.
Allogeneic hematopoietic stem cell transplantation (HSCT) involves:
Hematopoietic stem cell transplantation allows for maximal chemoradiotherapy and subsequent bone marrow regeneration. However, it also involves spec…