meRfi®-GM
MurA
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Contents
MurA is the Peptidoglycan (PGN) synthesis enzyme and interacts directly and specifically with the LPS synthesis enzyme LpxC protein / UDP-3-O-acyl-N-acetylglucosamine deacetylase, esp. in Pseudomonas aeruginosa
MurA was shown to stimulate LpxC activity in cells and in a purified system.
Direct interaction between LpxC and MurA is observed in diverse bacteria.
In …