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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Major depressive disorder / Major Depression / Depressive episode (MDD)

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Depression is common, costly, debilitating, and associated with increased risk of suicide. It is one of the leading global public health problems
Marwaha et al. 2023 The Lancet 401: 141-153

Major depressive disorder / Major Depression / Depressive episode (MDD), referred to as clinical depression, is a Mood disorders lasting 6 months or longer, which is associated with poor quality of life and considerable morbidity and mortality
Malhi & Mann 2018 Lancet 392: 2299-2312
Zhuo et al. 2019 Transl Psychiatry 9(1): 335
Cuijpers et al. 2020 Lancet Psychiatry 7(11): 925-927

Age, ethnic, hormonal, and sociocultural factors are also essential determinants to suffer from MDD and the presence of specific comorbidities and chronic disorders
Mckeever et al. 2017 Psychiatr.…

References (Sources)

Analysis of gut microbiota and intestinal integrity markers of inpatients with major depressive disorder.
Liskiewicz et al. 2021 Prog. Neuropsychopharmacol. Biol. Psychiatry 106: 110076
Depression and other common mental disorders: global health estimates
World Health Organization 2017 Licence: CC BY-NC-SA 3.0 IGO
Depression in adolescence
Thapar et al. 2012 Lancet 379(9820): 1056-67
Global burden of diseases, injuries, and risk factors for young people’s health during 1990–2013: a systematic analysis for the global burden of disease study 2013
Mokdad et al. 2016 Lancet 387(10036): 2383-401
Metabolic syndrome and metabolic abnormalities in patients with major depressive disorder: A meta-analysis of prevalences and moderating variables
Vancampfort et al. 2014 Psychol. Med. 44: 2017-2028
Suicidal ideation, suicide attempts and completed suicide in adolescents: neuro-biological aspects
Sarchiapone et al. 2015 Biol Aspects Suicidal Behav 30: 11-20
The rise and fall of MRI studies in major depressive disorder
Zhuo et al. 2019 Transl Psychiatry 9(1): 335

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Major depressive disorder - Wikipedia
https://www.who.int/news-room/fact-sheets/detail/adolescents-health-risks-and-solutions)