NCT02496390 - Fecal Microbiota Transplantation (FMT) allogenic vs Fecal Microbiota Transplantation (FMT) autologous & Non-Alcoholic Fatty Liver Disease (NAFLD) / Metabolic dysfunction-associated fatty liver disease (MAFLD)

Background:

Non-Alcoholic Fatty Liver Disease (NAFLD) / Metabolic dysfunction-associated fatty liver disease (MAFLD) is a disorder linked to obesity that is rapidly becoming more common and is viewed as the liver-related aspect of metabolic syndrome. The gut microbiota is crucial for metabolism and maintaining the integrity of the gut barrier. Research has shown that there are differences in the microbiota between individuals with NAFLD and those who are healthy, as well as increased intestinal permeability in NAFLD patients. Fecal microbiota transplantation (FMT) is a technique that can modify the gut microbiome. The hypothesis is that administering F…