meRfi®-GM
Butyrate / Butyric acid & Histone Deacetylase (HDAC) inhibition
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The functions of butyrate including inhibition of histone deacetylase, decrease tumorigenesis
n-Butyrate also acts as a modulator of colonic macrophages via Histone Deacetylase Inhibition, which leads to downregulation of pro-inflammatory response in vitro and in vivo

- Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases
- Butyrate conditions human Dendritic cells to Prime Type 1 regulatory T cells via both histone Deacetylase inhibition and G Protein-coupled receptor 109A signaling
- Emerging Frontiers in Microbiome EngineeringReview
- Inhibition of histone deacetylase activity by butyrate
- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
- The microbiome and its potential as a cancer preventive intervention
- The role of the gut microbiota in nutrition and health