Escherichia coli Nissle 1917 / E. coli Nissle 1917 (EcN) (genetically modified)

Genetically modified E. coli Nissle 1917 expressing anti‑inflammatory cytokines or metabolite‑degrading enzymes (e.g., phenylalanine‑degrading variants for phenylketonuria).
Zhang L, Chen N, Chen H, Tang C, Wang J, Wang Y, Zhang Y, Guo H, Yuan J. Recent advances of engineered probiotics for therapeutic applications. Biodes Res. 2025 Jul 15;7(3):100039