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Positive galectin-3 expression was observed in 84% of the gastric cancer cases. This does not apply to benign stomach cells near the tumor.
Galectin-3 expression varied depending on the histopathological type of gastric carcinoma.
Galectin-3 expression was observed significantly stronger in metastatic lymph nodes than in the primary gastric cancers, and also in these cases among histological subtypes, only in poorly differentiated adenocarcinoma, the expression of galectin-3 in metastatic lymph nodes was stronger than the primary cancer.
Galectin-3 may serve as a biomarker for gastric cancer.
Miyazaki et al. 2002 …