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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Stem-like CD8+ T cells (CD8+SL)

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Contents

= a subset of CD8+ T-Cell / Cytotoxic T Cell (CTL)
He et al. 2016 Nature 537: 412–428
Im et al. 2016 Nature 537: 417–421
Leong et al. 2016 Nat. Immunol. 17: 11871196
Utzschneider et al. 2016 Immunity 45: 415–427
Wu et al. 2016b Sci Immunol. 1: eaai8593
Kratchmarov et al. 2018 Blood Adv. 2: 1685–1690
Siddiqui et al. 2019 Immunity 50: 195–211
(20)
Marx et al. 2023 Immunity 56: 813–828

TCF1 / HNF1 homeobox A (HNF1A) expression marks stem-like CD8+ T cells (CD8+SL)
Kratchmarov et al. 2018 Blood Adv. 2: 1685–1690

Stem-like CD8+ T cells (CD8+SL) express SLAM family member 6 (SLAMF6) (encoded by the [Slamf6 gene](brain://rkuDrpuDbUScwytvSIw…

References (Sources)

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles(+) follicular cytotoxic T cells control viral infection in B cell follicles
Leong et al. 2016 Nat. Immunol. 17: 11871196
Deﬁning CD8 + T cells that provide the proliferative burst after PD-1 therapy
Im et al. 2016 Nature 537: 417–421
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy
Siddiqui et al. 2019 Immunity 50: 195–211
T cell factor 1-expressing memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections
Utzschneider et al. 2016 Immunity 45: 415–427
TCF1 expression marks self-renewing human CD8+(+) T cells
Kratchmarov et al. 2018 Blood Adv. 2: 1685–1690
TCF1+ hepatitis C virus-speciﬁc CD8+ T cells are maintained after cessation of chronic antigen stimulation
Wieland et al. 2017 Nat. Commun. 8: 15050
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness
Wu et al. 2016b Sci Immunol. 1: eaai8593

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