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Galectins
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= a family of carbohydrate-binding proteins that recognize beta-galactosides.
Galectins were first identified in the mid-1970s, and currently, 15 mammalian galectins have been identified.
While all galectin members possess the carbohydrate recognition domain (CRD) that interacts with beta-galactoside, their regulatory functions vary in different DNA or RNA virus infections.
More and more studies report on the roles that galectins play in numerous types of cancer. These roles can be varied, as has been shown particularly for galectin-3.
Since galectins bind [beta-galactosid…