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Transforming growth factor-β-Activated Kinase 1 (TAK1)

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The activation of TAK1 resulted in the activation and transfer of different transcription factors, including NFKB, JNK, and AP1 (in the latter case: over MKK3/6 and p38MAPK activation) leading to pro-inflammatory cytokine production
Heidari et al. 2022 Journal of Neuroinflammation 19: 135

Additionally, TAK1 activated MKK4/7