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Gut microbiota & Neurodevelopment / Development of the nervous system in humans

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The gut microbiota plays a significant role in neurodevelopment through the microbiota-gut-brain axis, which regulates various physiological processes. This influence occurs through three pathways: the immune pathway, the neuronal pathway, and the endocrine/systemic pathway, with overlaps and crosstalks between them.

Accumulating studies have identified the role of the microbiota-gut-brain axis in neurodevelopmental disorders such as attention deficit hyperactivity disorder and Rett Syndrome
Dash et al. 2022 Front Cell Dev Biol. 10: 880544
Wang et al. 2023 Protein Cell. 14(10): 762-775

The gut microbiota can affect brain gene expression, neurotransmitters, and [microglia]…